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Nhờ lấy giúp bài báo khoa học
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Mấy bài interscience của đc Cường bị sao ấy nhỉ? click vào nó bảo không set được cookies. Cho title nhé.
The Carotenoid Pigment Zeaxanthin—A Review
M.G. Sajilata 1 , R.S. Singhal 1 , and M.Y. Kamat 1 1 Authors are with Food Engineering and Technology Dept., Inst. of Chemical Technology, Univ. of Mumbai, Matunga, Mumbai-400 019, India. Direct inquiries to author Singhal (E-mail: rekha@udct.org).
Copyright 2008 Institute of Food Technologists
ABSTRACT
ABSTRACT: Scientific evidence linking several diseases with diet has brought to light the beneficial effects of a number of natural food ingredients. Zeaxanthin is one such natural pigment emphasized for its critical role in the prevention of age-related macular degeneration (AMD), the leading cause of blindness. The review highlights zeaxanthin as a carotenoid pigment with promising nutraceutical implications, and enumerates the important plant and microbial sources for its production, the absorptive pathway of zeaxanthin in human system, and methods to assess its bioavailability besides other relevant aspects.
M.G. Sajilata 1 , R.S. Singhal 1 , and M.Y. Kamat 1 1 Authors are with Food Engineering and Technology Dept., Inst. of Chemical Technology, Univ. of Mumbai, Matunga, Mumbai-400 019, India. Direct inquiries to author Singhal (E-mail: rekha@udct.org).
Copyright 2008 Institute of Food Technologists
ABSTRACT
ABSTRACT: Scientific evidence linking several diseases with diet has brought to light the beneficial effects of a number of natural food ingredients. Zeaxanthin is one such natural pigment emphasized for its critical role in the prevention of age-related macular degeneration (AMD), the leading cause of blindness. The review highlights zeaxanthin as a carotenoid pigment with promising nutraceutical implications, and enumerates the important plant and microbial sources for its production, the absorptive pathway of zeaxanthin in human system, and methods to assess its bioavailability besides other relevant aspects.
[SIZE=+2]Engineered isoprenoid pathway enhances astaxanthin production in Escherichia coli[/SIZE]
Chia-Wei Wang, Min-Kyu Oh, James C. Liao[SIZE=-1] *[/SIZE]Department of Chemical Engineering, University of California, Los Angeles, California 90095-1592
email: James C. Liao (liaoj@ucla.edu)[SIZE=-1]*[/SIZE]Correspondence to James C. Liao, Department of Chemical Engineering, University of California, Los Angeles, California 90095-1592
Keywords
isoprenoids; astaxanthin; isopentenyl diphosphate isomerase; geranylgeranyl diphosphate; metabolic engineering
Abstract
The isoprenoid pathway is a versatile biosynthetic network leading to over 23,000 compounds. Similar to other biosynthetic pathways, the production of isoprenoids in microorganisms is controlled by the supply of precursors, among other factors. To engineer a host that has the capability to supply geranylgeranyl diphosphate (GGPP), a common precursor of isoprenoids, we cloned and overexpressed isopentenyl diphosphate (IPP) isomerase (encoded by idi) from Escherichia coli and GGPP synthase (encoded by gps) from the archaebacterium Archaeoglobus fulgidus. The latter was shown to be a multifunctional enzyme converting dimethylallyl diphosphate (DMAPP) to GGPP. These two genes and the gene cluster (crtBIYZW) of the marine bacterium Agrobacterium aurantiacum were introduced into E. coli to produce astaxanthin, an orange pigment and antioxidant. This metabolically engineered strain produces astaxanthin 50 times higher than values reported before. To determine the rate-controlling steps in GGPP production, the IDI-GPS pathway was compared with another construct containing idi, ispA (encoding farnesyl diphosphate (FPP) synthase in E. coli), and crtE (encoding GGPP synthase from Erwinia uredovora). Results show that the conversion from FPP to GGPP is the first bottleneck, followed sequentially by IPP isomerization and FPP synthesis. Removal of these bottlenecks results in an E. coli strain providing sufficient precursors for in vivo synthesis of isoprenoids. © 1999 John Wiley & Sons, Inc. Biotechnol Bioeng 62: 235-241, 1999.
Chia-Wei Wang, Min-Kyu Oh, James C. Liao[SIZE=-1] *[/SIZE]Department of Chemical Engineering, University of California, Los Angeles, California 90095-1592
email: James C. Liao (liaoj@ucla.edu)[SIZE=-1]*[/SIZE]Correspondence to James C. Liao, Department of Chemical Engineering, University of California, Los Angeles, California 90095-1592
Keywords
isoprenoids; astaxanthin; isopentenyl diphosphate isomerase; geranylgeranyl diphosphate; metabolic engineering
Abstract
The isoprenoid pathway is a versatile biosynthetic network leading to over 23,000 compounds. Similar to other biosynthetic pathways, the production of isoprenoids in microorganisms is controlled by the supply of precursors, among other factors. To engineer a host that has the capability to supply geranylgeranyl diphosphate (GGPP), a common precursor of isoprenoids, we cloned and overexpressed isopentenyl diphosphate (IPP) isomerase (encoded by idi) from Escherichia coli and GGPP synthase (encoded by gps) from the archaebacterium Archaeoglobus fulgidus. The latter was shown to be a multifunctional enzyme converting dimethylallyl diphosphate (DMAPP) to GGPP. These two genes and the gene cluster (crtBIYZW) of the marine bacterium Agrobacterium aurantiacum were introduced into E. coli to produce astaxanthin, an orange pigment and antioxidant. This metabolically engineered strain produces astaxanthin 50 times higher than values reported before. To determine the rate-controlling steps in GGPP production, the IDI-GPS pathway was compared with another construct containing idi, ispA (encoding farnesyl diphosphate (FPP) synthase in E. coli), and crtE (encoding GGPP synthase from Erwinia uredovora). Results show that the conversion from FPP to GGPP is the first bottleneck, followed sequentially by IPP isomerization and FPP synthesis. Removal of these bottlenecks results in an E. coli strain providing sufficient precursors for in vivo synthesis of isoprenoids. © 1999 John Wiley & Sons, Inc. Biotechnol Bioeng 62: 235-241, 1999.
Bài chú Cường:
Đinh Duy Thành
Senior Member
Các bác dán link Wiley chỉ copy đến hết cái ..../abstract là được, bỏ hết mấy cái sau dấu ? đi
Ví dụ link của bác Cường: http://www3.interscience.wiley.com/journal/119423783/abstractNói đâu bỏ đấy, đợi các bác đọc xong rồi xóa cho khỏi lạc đề
Nguyễn Trường Khoa
Senior Member
bài của chú Cường !!!
vucongphong
Senior Member
Nhờ lấy hộ bài báo:
"Correlation between yield and osmotic adjustment of peas (Pisum sativum L.) under drought stress"
B. Rodríguez-Maribonaa, J. L. Tenorioa, J. R. Condeb and L. Ayerbea
a Dpto. de Producción y Tecnología de Alimentos, CIT, INIA, Apdo. 8111, 280280-, Madrid, Spain
b Dpto. de Fitotecnia, EUITA, Ciudad Universitaria, 28040-, Madrid, Spain
Accepted 21 January 1991. ;
Available online 7 July 2003.
http://www.sciencedirect.com/scienc...f6ad722f3d13c5659b7&ie=/sdarticle.pdf:thanks:
"Correlation between yield and osmotic adjustment of peas (Pisum sativum L.) under drought stress"
B. Rodríguez-Maribonaa, J. L. Tenorioa, J. R. Condeb and L. Ayerbea
a Dpto. de Producción y Tecnología de Alimentos, CIT, INIA, Apdo. 8111, 280280-, Madrid, Spain
b Dpto. de Fitotecnia, EUITA, Ciudad Universitaria, 28040-, Madrid, Spain
Accepted 21 January 1991. ;
Available online 7 July 2003.
http://www.sciencedirect.com/scienc...f6ad722f3d13c5659b7&ie=/sdarticle.pdf:thanks:
Đinh Duy Thành
Senior Member
plantbiotechnology
Junior Member
Nhờ anh, em xa gần lấy giúp mình 2 bài này với:
http://www.ncbi.nlm.nih.gov/pubmed/15802970
http://www.ncbi.nlm.nih.gov/pubmed/17542753
Cảm ơn các bác nhiều.
http://www.ncbi.nlm.nih.gov/pubmed/15802970
http://www.ncbi.nlm.nih.gov/pubmed/17542753
Cảm ơn các bác nhiều.
Nguyễn Trường Khoa
Senior Member
bài 1 của bạn !!!
plantbiotechnology
Junior Member
Cảm ơn bạn Nguyễn Trường Khoa nhiều!
vucongphong
Senior Member
Nhờ lấy hộ bài báo
Nhờ lấy hộ bài báo sau:
Insulin receptor
SciBX 3(16); doi:10.1038/scibx.2010.497
Published online April 22 2010
http://www.nature.com/scibx/journal/v3/n16/pdf/scibx.2010.497.pdf
Thanks you very much!
Nhờ lấy hộ bài báo sau:
Insulin receptor
SciBX 3(16); doi:10.1038/scibx.2010.497
Published online April 22 2010
http://www.nature.com/scibx/journal/v3/n16/pdf/scibx.2010.497.pdf
Thanks you very much!
vucongphong
Senior Member
Nhờ lấy hộ bài báo sau
[Nhờ lấy hộ bài báo sau:
Insulin receptor
SciBX 3(16); doi:10.1038/scibx.2010.497
Published online April 22 2010
http://www.nature.com/scibx/journal/...x.2010.497.pdf
Thanks you very much!
[Nhờ lấy hộ bài báo sau:
Insulin receptor
SciBX 3(16); doi:10.1038/scibx.2010.497
Published online April 22 2010
http://www.nature.com/scibx/journal/...x.2010.497.pdf
Thanks you very much!
Trương Xuân Đại
Senior Member
Nhờ anh, chị, em lấy giúp 2 bài này. Cảm ơn rất nhiều.
http://www.theriojournal.com/article/S0093-691X(01)00483-6/abstract
http://www.animalreproductionscience.com/article/PIIS0378432009001626/fulltext
http://www.theriojournal.com/article/S0093-691X(01)00483-6/abstract
http://www.animalreproductionscience.com/article/PIIS0378432009001626/fulltext
Trần Thiện Toàn
Senior Member
Vui lòng lấy giúp mình bài này nhé, thank you.
http://www.cell.com/abstract/S0092-8674(10)00491-5
http://www.cell.com/abstract/S0092-8674(10)00491-5
Hà Thị Minh Thi
Senior Member
Nhờ các bạn lấy giúp mình bài báo này với. Cảm ơn các bạn nhiều!
http://www.springerlink.com/content/px4822g800100x71/
http://www.springerlink.com/content/px4822g800100x71/
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