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Two pores better than one

Tuần này tờ Nature có hai bài khá hấp dẫn liên quan đến Sinh học tế bào và sinh học phát triển. Mời các bạn có hứng thú hãy tham gia chuyển ngữ các bài này vừa giúp bạn nâng cao English vừa để tiếp cận khoa học thế giới.


Nature 438, 299-300 (17 November 2005) | doi:10.1038/438299a

Cell biology: Two pores better than one?

Arnold J. M. Driessen1

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The movement of proteins through a cell's membrane requires a dedicated molecular machine. A glimpse of this apparatus in action shows that it has two channels, and hints at how these pores might be regulated.

A cell's membrane bristles with proteins that sense and communicate with its environment, and the cell secretes other proteins to send messages farther afield. To reach their destination, these proteins must travel from the aqueous environment of the cytoplasm where they are synthesized, through the seemingly impenetrable boundary of the lipid membrane. To ease the proteins' emigration, cells use a specialized protein complex called a translocase to direct proteins across or into the membrane. On page 318 of this issue, Mitra et al.1 report the structure of this remarkable complex caught in the act of inserting a newly synthesized protein into the membrane.

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